Quetiapine sulfoxide

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CAS NO:

329216-63-9

包装与价格：

产品名称

Quetiapine S-oxide

产品介绍

Quetiapine sulfoxide (Quetiapine S-oxide) 是 Quetiapinem 的主要代谢产物。Quetiapinem 是第二代抗精神病药。Quetiapine 是一种 5-HT 受体激动剂，也是一种多巴胺受体 (dopamine receptor) 拮抗剂。

生物活性	Quetiapine sulfoxide (Quetiapine S-oxide) is a main metabolite of Quetiapinem. Quetiapine is a second-generation antipsychotic^[1]. Quetiapine is a 5-HT receptors agonist and adopamine receptor antagonist^[2].
体内研究 (In Vivo)	The C_maxvalue (mean±SD) is estimated for Quetiapine sulfoxide (77.3±32.4 ng/mL). The AUC_lastvalue is estimated for Quetiapine sulfoxide (1,286±458 ngoh/mL). For Quetiapine sulfoxide, metabolic ratio decreases with time, from 119% on average 2 hours after dosing to 30% on average 72 hours after dosing^[1].
分子量	399.51
Formula	C₂₁H₂₅N₃O₃S
CAS 号	329216-63-9
中文名称	喹硫平亚砜
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.