Amlodipine-1,1,2,2-d4 maleate is the deuterium labeled Amlodipine. Amlodipine, an antianginal agent and an orally active dihydropyridinecalcium channelblocker, works by blocking the voltage-dependent L-type calcium channels, thereby inhibiting the initial influx of calcium. Amlodipine can be used for the research of high blood pressure andcancer^[1][2][3].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

528.97

C₂₄H₂₅D₄ClN₂O₉

1185246-15-4

氨氯地平 d4 (马来酸盐)

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.