CAS NO: | 1093108-50-9 |
包装 | 价格(元) |
10 mM * 1 mL in DMSO | 电议 |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
100mg | 电议 |
200mg | 电议 |
500mg | 电议 |
生物活性 | BI-671800 is a highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells(DP2/CRTH2), withIC50values of 4.5 nM and 3.7 nM for PGD2 binding to CRTH2 in hCRTH2 and mCRTH2 transfected cells, respectively[1]. BI-671800 has potential for the treatment of poorly controlled asthma[2]. | ||||||||||||||||
IC50& Target[1] |
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体外研究 (In Vitro) | BI-671800 (compound A) exhibits low nM potency as an antagonist of human or mouse CRTH2 in transfected cells[1]. | ||||||||||||||||
体内研究 (In Vivo) | BI-671800 (compound A, 0.1-10 mg/kg, i.g.) shows significant inhibition of AHR in mice[1].
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Clinical Trial | |||||||||||||||||
分子量 | 501.50 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C25H26F3N5O3 | ||||||||||||||||
CAS 号 | 1093108-50-9 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) | ||||||||||||||||
溶解性数据 | In Vitro: DMSO : 135 mg/mL(269.19 mM;Need ultrasonic) 配制储备液
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以下溶剂前显示的百
*以上所有助溶剂都可在本网站选购。 |