MRTX-EX185 是负载 GDP 的KRAS和KRAS(G12D)的有效抑制剂,对 KRAS(G12D) 的IC50值为 90 nM。MRTX-EX185 还结合 GDP 负载的HRAS。
生物活性 | MRTX-EX185 is a potent inhibitor ofGDP-loaded KRASandKRAS(G12D), with anIC50of 90 nM for KRAS(G12D). MRTX-EX185 also bindsGDP-loaded HRAS[1]. |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |