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AM12
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
AM12图片
CAS NO:2387510-84-9
包装与价格：
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
AM12 抑制镧系元素诱发的TRPC5活性，IC50为 0.28 μM。
生物活性

AM12 inhibits Lanthanide-evokedTRPC5activity with anIC50of 0.28 μM[1].

IC50& Target

IC50: 0.28 μM (TRPC5)[1]

体外研究
(In Vitro)

AM12 also inhibits TRPC5 activity evoked by the agonist (-)-Englerin A[1].
AM12 also inhibits TRPC4 channels similarly. AM12 inhibits TRPC5 and TRPC4 channels via a site accessible from the extracellular face of the membrane, acting directly on either the channel or a site closely associated with it[1].
AM12 also inhibits Ca2+entry evoked by Gd3+. AM12 inhibits the Gd3+-evoked Ca2+signal with an IC50of 0.28 μM. AM12 is slightly more potent than the natural product Galangin as an inhibitor of the Gd3+-evoked signal[1].

分子量

349.13

Formula

C15H9BrO5

CAS 号

2387510-84-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.