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Raclopride-d5 hydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Raclopride-d5 hydrochloride图片
CAS NO:1217623-85-2
包装与价格:
包装价格(元)
1mg电议
10mg电议
25mg电议

产品名称
雷氯必利 d5 (盐酸盐)
产品介绍
Raclopride-d5 (hydrochloride) 是 Raclopride 的氘代物。Raclopride 是一种多巴胺D2/D3受体拮抗剂,结合到D2D3受体,Ki分别为 1.8 nM 和 3.5 nM,但对 D1和 D4受体的亲和力非常低,Ki分别为 18000 nM 和 2400 nM。
生物活性

Raclopride-d5 (hydrochloride) is the deuterium labeled Raclopride. Raclopride is adopamine D2/D3receptorantagonist, which binds toD2andD3receptors with dissociation constants (Kis) of 1.8 nM and 3.5 nM, respectively, but has a very low affinity for D1and D4receptors with Kis of 18000 nM and 2400 nM, respectively[1][2].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

分子量

352.27

Formula

C15H16D5Cl3N2O3

CAS 号

1217623-85-2

中文名称

雷氯必利 d5 (盐酸盐)

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.