S1427 是一种反苯环丙胺衍生的LSD1抑制剂,IC50为 390 nM,Ki为 80 nM。S1427 抑制 hERG 通道,且具有微粒体稳定性。抑制 LSD1 可减少癌细胞的增殖。
生物活性 | S1427 is a tranylcypromine-derivedLSD1inhibitor with theIC50of 390 nM andKiof 80 nM. S1427 exhibits desirable hERG channel inhibition and microsomal stability profiles. Inhibition of LSD1 partially reduces the proliferation ofcancercells[1]. |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |