CAS NO: | 2368870-39-5 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
生物活性 | Galegine hydrochloride, a guanidine derivative, contributes to weight loss in mice. Guanidine hydrochloride is the compound derived fromG. officinalis, which gave rise to the biguanides, metformin and phenformin. Galegine hydrochloride activatesAMPKin 3T3-L1 adipocytes and L6 myotubes, as well as in the H4IIE rat hepatoma and HEK293 human kidney cell lines. Galegine hydrochloride hasantibacterialactivity, with minimum inhibitory concentration of 4 mg/L againstStaphylococcus aureusstrains[1][2]. | ||||||||||||||||
体外研究 (In Vitro) | Pre-treatment with Galegine hydrochloride (10 μM-3 mM; 5 h) produces a concentration-dependent stimulation of insulin-independent glucose uptake by 3T3-L1 adipocytes without any effect on cell viability. Incubation with Galegine hydrochloride (1 μM-1 mM, 5 h) produces a concentration-dependent stimulation of glucose uptake into L6 myotubes, again without any effect on cell viability[1]. | ||||||||||||||||
体内研究 (In Vivo) | Galegine hydrochloride (63 mg/kg; feed; daily for 11 days) produces a significant reduction in body weight[1].
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分子量 | 163.65 | ||||||||||||||||
Formula | C6H14ClN3 | ||||||||||||||||
CAS 号 | 2368870-39-5 | ||||||||||||||||
结构分类 |
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来源 |
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运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. | ||||||||||||||||
溶解性数据 | In Vitro: H2O : 43.33 mg/mL(264.77 mM;Need ultrasonic) DMSO : 5.2 mg/mL(31.78 mM;Need ultrasonic) 配制储备液
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