CAS NO: | 7361-61-7 |
包装 | 价格(元) |
10mM (in 1mL DMSO) | 电议 |
100mg | 电议 |
500mg | 电议 |
Cas No. | 7361-61-7 |
别名 | 赛拉嗪,BAY 1470 |
化学名 | N-(2,6-dimethylphenyl)-5,6-dihydro-4H-1,3-thiazin-2-amine |
Canonical SMILES | CC1=C(C(=CC=C1)C)NC2=NCCCS2 |
分子式 | C12H16N2S |
分子量 | 220.33 |
溶解度 | ≥ 9.8mg/mL in DMSO,insoluble in water and in alkali solutions |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Xylazine is a strong agonist of α2-adrenoceptor [1]. Xylazine has been reported to stimulate the proliferation of rat thymocytes in vivo (at doses of 2.5 mg/kg and 5 mg/kg) and in vitro (at concentration of 5 mM) [2]. In the analgesic testing, Xylazine has shown a significant prolongation of the analgesic effects in the presence of naloxine in 40 and 50 mins. In addition, Xylazine has also shown the inhibitory effect in the mouse vas deferens bioassay with the IC50 value of 18nM. Furthermore, Xylazine has displayed a potent specific [3H]-dihydromorphine binding inhibition with the IC50 value of 8μM in opiate receptor binding test [1]. References: |