Pyripyropene A is a potent and specific inhibitor of sterol O-acyltransferase 2 (SOAT2) or acyl-coenzyme A:cholesterol acyltransferase 2 (ACAT2) with the potential to be used for atherosclerosis. ACAT is a key enzyme for cholesteryl ester accumulation in atherogenesis,
lipoprotein formation in liver, and cholesterol absorption from
intestines, all of which are events that contribute to the
atherosclerotic process.
纯度:≥98%
CAS:147444-03-9