Spantide I 是一种 P 物质类似物,是一种选择性 NK1 受体拮抗剂,对 NK1 和 NK2 受体的 Ki 值分别为 230 nM 和 8150 nM。
Cas No. | 91224-37-2 |
化学名 | (S,Z)-N'1-((2R,3Z,5S,6Z,8R,9Z,11S,12Z,14S)-8-((1H-indol-3-yl)methyl)-5-benzyl-3,6,9,12-tetrahydroxy-14-(hydroxy(imino)methyl)-1-(1H-indol-3-yl)-11-isobutyl-16-methyl-4,7,10,13-tetraazaheptadeca-3,6,9,12-tetraen-2-yl)-2-((Z)-((S)-2-((Z)-(((S)-1-((S)-6-amin |
Canonical SMILES | CC(C[C@@](/N=C(O)/[C@](/N=C(O)/[C@@](/N=C(O)/[C@](/N=C(O)/[C@@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@]1([H])CCCN1C([C@](/N=C(O)/[C@]2([H])CCCN2C([C@@](N)([H])CCCNC(N)=N)=O)([H])CCCCN)=O)([H])CCC(O)=N)([H])CCC(O)=N)([H])CC3=CNC4=CC=CC=C34)([H])CC5=CC=CC=C5 |
分子式 | C75H108N20O13 |
分子量 | 1497.79 |
溶解度 | Soluble to 1 mg/ml in Water |
储存条件 | Desiccate at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |