Mesaconitine is the main active component of genus aconitumplants. IC50 value: Target: in vitro: In HUVECs, 30 microM mesaconitine increased the [Ca(2+)](i) level in the presence of extracellular CaCl(2) and NaCl, and the response was inhibited by KBR7943. Mesaconitine increased intracellular Na(+) concentration level in HUVECs. The [Ca(2+)](i) response by mesaconitine was inhibited by 100 microM D-tubocurarine [1]. Mesaconitine at 30 microM inhibited 3 microM phenylephrine-induced contraction in the endothelium-intact, but not endothelium-denuded, aortic rings [2]. MA promoted the alpha-MT-induced decrease in NE levels in hippocampus, medulla oblongata plus pons and spinal cord [3].

631.71

Solid

C₃₃H₄₅NO₁₁

2752-64-9

中乌头碱；新乌头碱；美沙乌头碱；新乌碱

• Alkaloids
• Isoquinoline Alkaloids

• Plants
• Ranunculaceae
• Aconitum carmichaeliDebx.

Room temperature in continental US; may vary elsewhere.

Ethanol : 4.62 mg/mL(7.31 mM;Need ultrasonic)

H₂O :< 0.1 mg/mL(insoluble)

DMSO :< 1 mg/mL(insoluble or slightly soluble)

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80℃, 6 months; -20℃, 1 month。-80℃ 储存时，请在 6 个月内使用，-20℃ 储存时，请在 1 个月内使用。