DBCO-(PEG2-VC-PAB-MMAE)2 is made by MMAE conjugated to the cleavable DBCO-(PEG2-VC-PAB)2 linker. Monomethyl auristatin E (MMAE), a highly potent tubulin inhibitor, is a toxin payload in antibody drug conjugate. References: [1]. Brian Lannutti, et al. Ror1 antibody immunoconjugates. WO2018237335A1.
纯度:≥98%
CAS:2259318-55-1