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L-Glutamic acid-1-13C
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
L-Glutamic acid-1-13C图片
CAS NO:81201-99-2
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议
200mg电议

产品名称
L-谷氨酸 1-13C
产品介绍
L-Glutamic acid-1-13C 是一种 13C 标记的 L-Glutamic acid。L-Glutamic acid 作为一种兴奋性氨基酸神经递质,为谷氨酸盐受体所有亚型(代谢型红藻氨酸、NMDA 和 AMPA)的激动剂。对DA从多巴胺能神经末梢释放的过程有激动作用。
生物活性

L-Glutamic acid-1-13C is the 13C-labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release ofDAfrom dopaminergic terminals.

IC50& Target

AMPA Receptor

 

NMDA Receptor

 

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

分子量

148.12

性状

Solid

Formula

C413CH9NO4

CAS 号

81201-99-2

中文名称

L-谷氨酸 1-13C

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)