CAS NO: | 1542098-94-1 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | DHQZ 36 is a potent inhibitor of retrograde trafficking. DHQZ 36 inhibitsLeishmaniaamazonensisinfectionin macrophages with anEC50of 13.63 μM. DHQZ 36 has potent anti-parasite activity[1]. |
IC50& Target | EC50: 13.63 μM (Leishmania amazonensis)[1] |
体外研究 (In Vitro) | With increasing concentrations of DHQZ 36 there is a significant diminution in the size of parasitophorous vacuoles (LPVs), vacuole sizes are reduced by 30% at 50 μM. These parasites also cause a reduction in the number of parasites per macrophage. Significant parasite loss is observed with as low as 5 μM after treatment with DHQZ 36. Parasites are unable to recover growth when treated with DHQZ 36 at concentrations at or above 12.5 μM[1]. |
分子量 | 384.44 |
Formula | C21H18F2N2OS |
CAS 号 | 1542098-94-1 |
运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |