包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | FPR2 agonist 2 is a potent and permeates the blood–brain barrierFPR2agonist with anEC50of 0.13 μM, 1.1 μM for FPR2 and FPR1, respectively. FPR2 agonist 2 inhibits the production of pro-inflammatory cytokines, counterbalances the changes in mitochondrial function, and inhibits caspase-3 activity[1]. | ||||||||
IC50& Target | EC50: 0.13 μM (FPR2); 1.1 μM (FPR1)[1] | ||||||||
体外研究 (In Vitro) | FPR2 agonist 2 (compound (S)-11l) (1-100 μM; 48 h) exhibits low cytotoxicity with an EC50value of 20.8 μM in N9 cells[1]. Cell Viability Assay[1]
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体内研究 (In Vivo) | FPR2 agonist 2 (1 mg/kg for i.v.; 10 mg/kg for i.p.) shows the ability to permeate the blood–brain barrier and to accumulate in the brain[1].
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分子量 | 446.45 | ||||||||
Formula | C25H20F2N4O2 | ||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |