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Thioridazine-d3 hydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Thioridazine-d3 hydrochloride图片
CAS NO:1189928-36-6
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
50mg电议

产品介绍
Thioridazine-d3 hydrochloride 是 Thioridazine 的氘代物。Thioridazine hydrochloride 是一种具有口服活性的多巴胺受体D2家族蛋白的拮抗剂,具有有效的抗焦虑活性。Thioridazine hydrochloride 也是一种有效的PI3K-Akt-mTOR信号通路的抑制剂,具有抗血管生成作用。Thioridazine hydrochloride 在多种类型的癌细胞中显示出抗增殖和凋亡诱导作用,对靶向癌症干细胞 (CSCs) 具有特异性。
生物活性

Thioridazine-d3 hydrochloride is the deuterium labeled Thioridazine. Thioridazine, an antagonist of thedopamine receptorD2family proteins, exhibits potent anti-psychotic and anti-anxiety activities. Thioridazine is also a potent inhibitor ofPI3K-Akt-mTORsignaling pathways with anti-angiogenic effect. Thioridazine shows antiproliferative andapoptosisinduction effects in various types ofcancercells, with specificity on targetingcancer stem cells(CSCs)[1][2][3][4].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

分子量

410.05

Formula

C21H24D3ClN2S2

CAS 号

1189928-36-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.