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Ledipasvir-d6
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Ledipasvir-d6图片
CAS NO:2050041-12-6
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
50mg电议
100mg电议

产品名称
GS-5885-d6
产品介绍
Ledipasvir-d6 (GS-5885-d6) 是 Ledipasvir 的氘代物。Ledipasvir (GS-5885) 是一种有效的HCV NS5A抑制剂,能够抑制 GT1a 和 GT1b 复制子,EC50值分别为 34 pM 和 4 pM。Ledipasvir 也是SARS-CoV 3CLpro的抑制剂,IC50为 1.62 μM。
生物活性

Ledipasvir-d6 (GS-5885-d6) is the deuterium labeled Ledipasvir. Ledipasvir (GS-5885) is an inhibitor of thehepatitis C virus NS5A, withEC50s of 34 pM and 4 pM against genotype 1a and 1b replicon, respectively. Ledipasvir is also aSARS-CoV3CLproinhibitor with anIC50of 1.62 μM[3].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

分子量

895.04

Formula

C49H48D6F2N8O6

CAS 号

2050041-12-6

中文名称

雷迪帕韦 d6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.