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A68930
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
A68930图片
CAS NO:130465-45-1
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
A68930 作为dopamine D1 receptor激动剂,可用于支气管扩张的研究。
生物活性

A68930, as adopamine D1 receptoragonist, can be used for the research of bronchiectasis[1].

IC50& Target

D1Receptor

 

体外研究
(In Vitro)

A68930 (1 μM; 5-60 minutes; 16HBE14o- or NCI-H292 cells) significantly increases phosphorylation of cAMP response element binding (CREB) protein[1].
A68930 (1 μM; 48 hours; NCI-H292 cells) induces MUC5AC mRNA expression and increases the mRNA data of MUC5AC and MUC5AC protein expression[1].
A68930 (1 μM; 20 minutes; NCI-H292 cells) significantly increases intracellular cAMP levels[1].

Western Blot Analysis[1]

Cell Line:16HBE14o- or NCI-H292 cells
Concentration:1 μM
Incubation Time:5~60 minutes
Result:Significantly increased phosphorylation of CREB.

RT-PCR[1]

Cell Line:NCI-H292 cells
Concentration:1 μM
Incubation Time:48 hours
Result:Induced MUC5AC mRNA expression.

Immunofluorescence[1]

Cell Line:NCI-H292 cells
Concentration:1 μM
Incubation Time:48 hours
Result:The mRNA data of MUC5AC, MUC5AC protein expression were increased.
分子量

271.31

Formula

C16H17NO3

CAS 号

130465-45-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.