Tartrazine 是偶氮型酸性染料,是橙黄色粉末,溶于水中呈黄色,常用作食品着色的合成柠檬黄色偶氮染料。
产品描述
Tartrazine is a food additive that belongs to a class of artificial dyes and contains an azo group; it has significant genotoxic effect , may be harmful to health and its prolonged use could trigger carcinogenesis.
体外活性
We assessed the cytotoxicity of Tartrazine by 3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide test and the response of DNA repair through comet assay (alkaline version). We used different concentrations of the dye, ranging from 0.25-64.0 mM. The results demonstrated that Tartrazine has no cytotoxic effects. However, this dye had a significant genotoxic effect at all concentrations tested. Although most of the damage was amenable to repair, some damage remained higher than positive control after 24 h of repair[2]
Cas No.
1934-21-0
分子式
C16H12N4NaO9S2
分子量
491.41
别名
Acid Yellow 23;酸性黄 23;FD&C Yellow No. 5;酒石黄
储存和溶解度
DMSO:45 mg/mL (84.21 mM),Need ultrasonic
H2O:45 mg/mL (84.21 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years