Chebulic acid 是一种分离自Terminalia chebula中的酚羧酸化合物，具有显著的抗氧化作用，它能够打破由晚期糖基化终产物 (AGEs) 诱导的蛋白质交联，阻碍 AGEs 的形成。它能够有效控制代谢参数升高、氧化应激和肾损害，支持其在糖尿病肾病中的有益作用。

Chebulic acid, a phenolcarboxylic acid compound isolated from Terminalia chebula, has potent anti-oxidant activity,which breaks the cross-links of proteins induced by advanced glycation end-products (AGEs) and inhibits the formation of AGEs.It has effects against the progression of AGE-induced endothelial cell dysfunction,may constitute a promising intervention agent against diabetic vascular complications

chebulic acid prevents the glycer-AGEs-induced ROS formation of LX-2 cells and collagen accumulation by ERK-phosphorylation-mediated Nrf2 nuclear translocation, which causes upregulation of antioxidant protein production[2].

23725-05-5

C14H12O11

356.24

DMSO:260 mg/mL (729.85 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years