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Coumarin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:91-64-5
包装与价格:
包装价格(元)
50 mg电议
1 mL*10 mM(in DMSO)电议

产品介绍
Coumarin 是中国北沙参中的一种主要生物活性成分,具有抗癌、抗炎和抗病毒等活性。它作为几种抗凝剂的前体具有临床价值,尤其是华法林。

产品描述

Coumarin is a chemical compound/poison found in many plants, notably in high concentration in the tonka bean, woodruff, and bison grass. It has clinical value as the precursor for several anticoagulants, notably warfarin.

体外活性

Coumarin is a fragrant organic chemical compound in the benzopyrone chemical class, which is a colorless crystalline substance in its standard state. Coumarin is a naturally occurring constituent of many plants and essential oils, including tonka beans, sweet clover, woodruff, oil of cassia, and lavender. Coumarin is a member of a class of compounds called benzopyrones. Coumarin compounds have been used to treat such diverse ailments as cancer, bums, brucellosis, and rheumatic disease, and they have been used as antispasmodics. Although coumarin itself has no anticoagulant properties, it is transformed into the natural anticoagulant dicoumarol by a number of species of fungi. This occurs as the result of the production of 4-hydroxycoumarin, then further into the actual anticoagulant dicoumarol, a fermentation product and mycotoxin. This substance is responsible for the bleeding disease known historically as "sweet clover disease" in cattle eating moldy sweet clover silage.[1]

Cas No.

91-64-5

分子式

C9H6O2

分子量

146.14

储存和溶解度

H2O:<1 mgml
Ethanol:28 mg/mL (191.6 mM)
DMSO:28 mg/mL (191.6 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years