Sodium Salicylate 是一种S6K的抑制剂，可抑制COX-2活性。它还是一种NF-Κb抑制剂，可降低炎症基因的表达，促进老化肌肉的修复。

Sodium salicylate, a metabolite of acetylsalicylic acid, can inhibit NF-kB and reduce oxidative stress.

Sodium salicylate acts as non-steroidal anti-inflammatory drug (NSAID), and induces apoptosis in cancer cells and also necrosis. Sodium salicylate inhibits the activation of NF-kappa B, and also inhibits NF-kappa B-dependent transcription from the Ig kappa enhancer and the human immunodeficiency virus (HIV) long terminal repeat (LTR) in transfected T cells. [1] Sodium salicylate also induces apoptosis via p38 MAPK and inhibits TNF-induced JNK/stress-activated protein kinase activation. [2]

54-21-7

C7H5NaO3

160.104

Salicylic acid sodium salt;2-Hydroxybenzoic acid sodium salt;水杨酸钠

DMSO:30 mg/mL (187.4 mM)
Ethanol:<1 mgml
H2O:29 mg/mL (181.1 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years