NDT 9513727 是一种有效的、选择性的、具有口服活性和竞争性的人 C5aR(C5a 受体)反向激动剂,IC50 为 11.6 nM。
Cas No. | 439571-48-9 |
化学名 | 1-(benzo[d][1,3]dioxol-5-yl)-N-(benzo[d][1,3]dioxol-5-ylmethyl)-N-((1-butyl-2,4-diphenyl-1H-imidazol-5-yl)methyl)methanamine |
Canonical SMILES | CCCCN(C(C1=CC=CC=C1)=N2)C(CN(CC3=CC4=C(OCO4)C=C3)CC5=CC6=C(OCO6)C=C5)=C2C7=CC=CC=C7 |
分子式 | C36H35N3O4 |
分子量 | 573.68 |
溶解度 | <57.37mg/ml in DMSO;<57.37mg/ml in ethanol |
储存条件 | Store at -20℃ |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |