L-371,257 是催产素受体的竞争性拮抗剂，pA2 为 8.4，Ki 为 19 nM。 L-371,257 对加压素受体 1a 的 Ki 值为 3.7 nM。

L-371,257 is a competitive antagonist of oxytocin receptor with pA2 of 8.4 and Ki of 19 nM. L-371,257 shows a Ki of 3.7 nM for vasopressin receptor 1a.

L-371,257 (0.5 and 1.0 mg/kg; i.p.) stimulates weight gain (10.5 g) relative to vehicle treatment (4.7 g) in rats[3].

162042-44-6

C28H33N3O6

507.58

DMSO:8.1mg/mL (16mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years