Gentamicin sulfate是一种广谱氨基糖苷类抗生素,用于抑制敏感生物体中的蛋白质合成。
产品描述
Gentamycin Sulfate is a wide-spectrum, aminoglycoside antibiotic used to inhibit protein synthesis in sensitive organisms.
体内活性
Gentamicin is the first choice aminoglycoside for the treatment of serious infections at present, with alternatives being amikacin, netilmicin, and tobramycin. Gentamicin preparations are commercially available in three forms, namely otic, ophthalmic, and topical based on the respective function to treat infections of ear canal, eye, and skin. Oral and injectable forms of gentamicin are found to exhibit effective antibacterial activity against Yersinia pestis as demonstrated in a mouse infection model[4]. Treatment with up to nine doses of methicillin or gentamicin shows an obvious reduction of bacteria on the foreign body[5].
Cas No.
1405-41-0
分子式
C21H45N5O11S
分子量
575.68
别名
Gentamycin sulfate;硫酸庆大霉素;SCH9724;NSC-82261
储存和溶解度
DMSO:Insoluble
H2O:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years