BAY 2416964 是一种可口服的芳基烃受体拮抗剂，IC50为 341 nM，可用于研究实体瘤。详细信息请参考专利文献 WO2018146010A1 中的化合物 192。

BAY 2416964 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist extracted from patent WO2018146010A1 (example 192, IC50: 341 nM). It has the potential for cancer treatment.

BAY 2416964 induces AHR-regulated gene CYP1A1 expression in human monocytic U937 cells (IC50: 4.3 nM).

2242464-44-2

C18H18ClN5O3

387.82

DMSO:250 mg/mL (644.63 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years