Bucolome 是一种 CYP2C9 抑制剂,具有排尿酸和抗炎活性。
产品描述
Bucolome is a CYP2C9 inhibitor with uricosuric and anti-inflammatory activity.
体外活性
In studies with recombinant human cytochrome P-450 2C9 and liver microsomes, Bucolome is a potent mixed-type inhibitor for (S)-warfarin 7-hydroxylation, with Ki of 8.2 and 20.2 microM, respectively[1].
Cas No.
841-73-6
分子式
C14H22N2O3
分子量
266.34
别名
Paramidine;布可隆;Bucolom;Paramidin;Bucolomum;5-Butyl-1-cyclohexylbarbituric acid
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years