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Sinensetin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Sinensetin图片
CAS NO:2306-27-6
包装与价格:
包装价格(元)
20 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
甜橙素
Pedalitin permethyl ether
产品介绍
Sinensetin是从水果中发现的一种甲基化黄酮,有很强的抗血管和抗炎症的能力。

产品描述

Sinensetin is a methylated flavone found in certain citrus fruits. pocess potent antiangiogenesis and anti-inflammatory, sinensetin enhances adipogenesis and lipolysis.

体外活性

Sinensetin promots adipogenesis in 3T3-L1 preadipocytes growing in incomplete differentiation medium, sinensetin enhances adipogenesis and lipolysis by increasing cAMP levels. Sinensetin shows anti-inflammatory activity by regulating the protein level of inhibitor κB-α (IκB-α).

体内活性

Sinensetin has the most potent antiangiogenesis activity and the lowest toxicity, inhibits angiogenesis by inducing cell cycle arrest in the G0/G1 phase in HUVEC culture and downregulating the mRNA expressions of angiogenesis genes flt1, kdrl, and hras in zebrafish.

Cas No.

2306-27-6

分子式

C20H20O7

分子量

372.373

别名

甜橙素;Pedalitin permethyl ether

储存和溶解度

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years