ChX710可以引发 I 型干扰素对细胞溶质 DNA 的反应，其特异性细胞干扰素刺激基因 (ISG) 诱导 ISRE 启动子序列和干扰素调节因子 (IRF) 3 的磷酸化。

ChX710 could prime the type I interferon response to cytosolic DNA, which specific cellular Interferon-Stimulated Genes (ISGs), induces the ISRE promoter sequence, and the phosphorylation of Interferon Regulatory Factor (IRF) 3.

The treatment of ChX710 efficiently prime the cellular response to DNA transfection via STING as assessed by strong synergistic effects on IFN-β expression at both transcriptional and protein levels.

2438721-44-7

C18H21N5O

323.39

DMSO:20 mg/mL (61.84 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years