BMS-1是一种PD-1/PD-L1蛋白质/蛋白质相互作用的抑制剂，IC50为 6 到 100 nM。

PD1-PD-L1 inhibitor 1 (PD1-PD-L1-IN-1) is an inhibitor of the PD1-PD-L1 protein-protein interaction. It also acts as an immunomodulator. Programmed death ligand 1 (PD-L1) is a protein in humans that is encoded by the CD274 gene and the upregulation of PD-L1 allows Ys to evade the host immune system. High tumor expression of PD-L1 was associated with increased tumor aggressiveness and a 4.5-fold increased risk of death.

1675201-83-8

C29H33NO5

475.585

PD1-PDL1 inhibitor 1;PD-1/PD-L1 inhibitor 1

DMSO:29 mg/mL (60.98 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years