CASIN是选择性GTPase Cdc42抑制剂,IC50值是 2 uM。
产品描述
CASIN is a specific inhibitor of GTPase Cdc42 (IC50: 2 uM).
体外活性
CASIN (5 uM) could reduce the elevated level of active Cdc42 in aged primitive hematopoietic cells to the level in young cells.
体内活性
CASIN can reverse the aging-related and polarity phenotype of aged HSCs to that of young HSCs.
Cas No.
425399-05-9
分子式
C20H22N2O
分子量
306.41
别名
Pirl1-related Compound 2
储存和溶解度
DMSO:31 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years