Curculigoside 是仙茅中的主要皂苷，具有显著的抗氧化、抗骨质疏松、抗抑郁和神经保护作用。它通过调节JAK/STAT/NF-Κb信号传导途径，具有抗关节炎作用。

1. Curculigoside can prevent bone loss , improve osteogenesis and inhibit osteoclastogenesis of hAFSCs, suggesting its potential use to regulate hAFSC osteogenic differentiation for treating bone disorders. 2. Curculigoside can promote calcium deposition and increase the levels of ALP and Runx2 in osteoblasts under oxidative stress via anti-oxidative character. 3. Curculigoside possesses potent antioxidant properties against oxidative stress insults. can protect endothelial cells against oxidative injury induced by H2O2, suggesting that this compound may constitute a promising intervention against cardiovascular disorders.

85643-19-2

C22H26O11

466.43

仙茅苷;Curculigoside A

DMSO:84 mg/mL(180.1 mM)
Ethanol:84 mg/mL(180.1 mM)
Pyridine, Methanol, etc.:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years