Windorphen 是一种 Wnt 抑制剂，可选择性地消除 Wnt 信号传导。

Windorphen is a Wnt inhibitor that selectively abrogates the Wnt signaling.

Windorphen that selectively blocks the Wnt signal required for ventral development.?Windorphen exhibits remarkable specificity toward β-catenin-1 function, indicating that the two β-catenin isoforms found in zebrafish are not functionally redundant.?Windorphen is a selective inhibitor of p300 histone acetyltransferase, a coactivator that associates with β-catenin.?Finally, windorphen robustly and selectively kills cancer cells that harbor Wnt-activating mutations, supporting the therapeutic potential of this Wnt inhibitor class.

19881-70-0

C17H15ClO3

302.75

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years