Cardiogenol C hydrochloride 是一种细胞渗透性嘧啶诱导剂，能够促使 ESCs 分化为心肌细胞。在有限的可塑性范围内，它可以对已经沿袭的祖细胞类型产生心肌生成效应，是一种心肌生成试剂，在动物模型中可以用作细胞移植研究中提高心脏修复的工具。

Cardiogenol C hydrochloride can induces the differentiation of ESCs into cardiomyocytes (EC50= 100 nM).

Cardiogenol C could induce HBPCs to express transcription factors GATA4, Nkx2.5 and Tbx5, which are early specific markers for pre-cardiomyogenic cells[1].

Used GMEM plus 5 μM Cardiogenol C and 7.5% ESQ-FBS.?The cultures were harvested at different day-intervals after induction for immunohistochemistry, semi-quantitative RT-PCR analysis, western blot analysis and comparative proteomic[1].

1049741-55-0

C13H17ClN4O2

296.76

2-[[2-[(4-甲氧基苯基)氨基]-4-嘧啶基]氨基]乙醇盐酸盐;Cardiogenol C HCl;Cardiogenol C

DMSO:59 mg/mL (198.82 mM)
H2O:2 mg/mL (6.74 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years