Thevetiaflavone 是一种来自 Wikstroemia indica 的天然类黄酮,可抑制乳酸脱氢酶从细胞质中泄漏并提高细胞活力。
产品描述
Thevetiaflavone is a natural flavonoid from Wikstroemia indica that inhibits the leakage of lactate dehydrogenase from the cytoplasm and increases cell viability.
体外活性
Thevetiaflavone reduces ROS overproduction and ameliorates ROS-mediated mitochondrial dysfunction, including collapse of mitochondrial membrane potential and opening of mitochondrial permeability transition pores, thereby reducing intracellular Ca2+ levels. Thevetiaflavone up-regulates the expression of Bcl-2, down-regulates the expression of Bax and caspase-3 and increases the activity of caspase-3 to inhibit the apoptosis of PC12 cells[1].
Cas No.
29376-68-9
分子式
C16H12O5
分子量
284.26
别名
2-Genistein-5-methyl ether;Apigenin-5-methyl ether
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years