CP 31398 dihydrochloride 是一种 p53 稳定剂，可稳定 p53 的活性构象并促进具有突变型或野生型 p53 的癌细胞系中的 p53 活性。

CP 31398 dihydrochloride is a p53 stabilizer which stabilizes the active conformation of p53 and promotes p53 activity in cancer cell lines with mutant or wild-type p53.

CP-31398 (15 μg/mL, 20 hours) could induce apoptosis and cell cycle arrest in SW480 cells[1]. CP-31398 (36.75 μM, 16 h) induces p21 in p53-mutant cells[2].

1217195-61-3

C22H28Cl2N4O

435.39

CP 31398 dihydrochloride

DMSO:6 mg/ml (13.78 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years