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(RS)-AMPA
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
(RS)-AMPA图片
CAS NO:77521-29-0
包装:10 mg
市场价:3500元

产品名称
(±)-AMPA
产品介绍
(RS)-AMPA 是谷氨酸的一种类似物,对兴奋性神经递质 L-谷氨酸有激动作用。它不会干扰海藻酸或 NMDA 受体的结合位点。

产品描述

(RS)-AMPA is a glutamate analog. (RS)-AMPA is an agonist of effective and selective excitatory neurotransmitter L-glutamic acid.

体外活性

(RS)-AMPA exerts its depolarizing effects by activating glutamate/quisqualate receptors without affecting NMDA receptors. (RS)-AMPA causes an increase of the discharge rate of spontaneously firing neurones or sometimes evoked a short burst of action potentials in silent cells. The depolarization by (RS)-AMPA is clearly dose-dependent, although there is great variability of effects between individual neurones. (RS)-AMPA (10-3-10-4 M) induces depolarizations of cultured rat spinal and brainstem neurones. Application of (RS)-AMPA at 10-5 M produces only small depolarizations (3-7 mV), whereas, at 10-4 M, the amplitudes of the depolarizations ranged from 4 to 33 mV [1].

Cas No.

77521-29-0

分子式

C7H10N2O4

分子量

186.17

别名

(±)-AMPA

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years