(RS)-AMPA 是谷氨酸的一种类似物，对兴奋性神经递质 L-谷氨酸有激动作用。它不会干扰海藻酸或 NMDA 受体的结合位点。

(RS)-AMPA is a glutamate analog. (RS)-AMPA is an agonist of effective and selective excitatory neurotransmitter L-glutamic acid.

(RS)-AMPA exerts its depolarizing effects by activating glutamate/quisqualate receptors without affecting NMDA receptors. (RS)-AMPA causes an increase of the discharge rate of spontaneously firing neurones or sometimes evoked a short burst of action potentials in silent cells. The depolarization by (RS)-AMPA is clearly dose-dependent, although there is great variability of effects between individual neurones. (RS)-AMPA (10-3-10-4 M) induces depolarizations of cultured rat spinal and brainstem neurones. Application of (RS)-AMPA at 10-5 M produces only small depolarizations (3-7 mV), whereas, at 10-4 M, the amplitudes of the depolarizations ranged from 4 to 33 mV [1].

77521-29-0

C7H10N2O4

186.17

(±)-AMPA

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years