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SEP-363856 hydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
SEP-363856 hydrochloride图片
CAS NO:1310422-41-3
包装与价格:
包装价格(元)
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议
500 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
SEP-856 hydrochloride
产品介绍
SEP-363856 hydrochloride 是一种口服活性和 CNS 活性的精神药物,具有独特的非 D2/5-HT2A 作用机制,发挥其抗精神病样作用,具有治疗精神分裂症的潜力。

产品描述

SEP-363856 hydrochloride is an agent of orally active and CNS active psychotropic with a unique, non-D2/5-HT2A mechanism of action, exerts its antipsychotic-like effects, has the potential to treatment of schizophrenia.

体外活性

SEP-856 (10μM) specifically inhibits α2A, α2B, D2, 5-HT1A, 5-HT1B, 5-HT1D, 5-HT2A, 5-HT2B, 5-HT2C and 5-HT7>50% receptor.

体内活性

SEP-856 (0.3, 1 and 10 mg/kg, i.p.) is CNS active. SEP-856 exhibits a behavioral signature similar to known antipsychotic drugs.PCP-induced hyperactivitysignificantly reduced by SEP-856 (0.3, 1 and 10 mg/kg, orally once) . Oral SEP-856 administration (1, 3 and 10 mg/kg) produces a dosedependent decrease in REM sleep, increase in latency to REM sleep and increase in cumulative wake (W) time.

Cas No.

1310422-41-3

分子式

C9H14ClNOS

分子量

219.73

别名

SEP-856 hydrochloride

储存和溶解度

DMSO:62.5 mg/mL (284.44 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years