BACE1-IN-2 is a BACE1 inhibitor (IC50: 22 nM).

BACE1-IN-2 (Compound 3) is 10-fold more potent toward BACE1 than BACE2, inhibition of which may lead to hair depigmentation. BACE1-IN-2 inhibits hAβ42 cells (IC50: 6.0 nM).

1352416-78-4

C19H15F4N5O2

421.35

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years