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N-Methyl-4-pyridone-5-carboxamide
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
N-Methyl-4-pyridone-5-carboxamide图片
CAS NO:769-49-3
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议
100mg电议

产品介绍
A metabolite of nicotinic acid and a uremic toxin
Cas No.769-49-3
别名N1-甲基-4-吡啶酮-3-甲酰胺
Canonical SMILESO=C(C1=CN(C)C=CC1=O)N
分子式C7H8N2O2
分子量152.2
溶解度Ethanol: Slightly soluble,PBS (pH 7.2): 5 mg/ml
储存条件-20буC
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

N-Methyl-4-pyridone-5-carboxamide is a metabolite of nicotinic acid and a uremic toxin.1,2Plasma levels of N-methyl-4-pyridone-5-carboxamide are increased and positively correlated with serum levels of malondialdehyde (MDA) in patients with chronic kidney disease (CKD).2

1.Chang, M.L.W., and Johnson, B.C.N-Methyl-4-pyridone-5-carboxamide as a metabolite of nicotinic acid in man and monkeyJ. Biol. Chem.2362096-2098(1961) 2.Rutkowski, P., S?ominska, E.M., Szo?kiewicz, M., et al.Relationship between uremic toxins and oxidative stress in patients with chronic renal failureScand. J. Urol. Nephrol.41(3)243-248(2007)