K 579 是一种有效且具有口服活性的二肽基肽酶 IV 抑制剂。
| Cas No. | 440100-64-1 |
| 化学名 | (2S)-1-[2-[(4-methyl-1-pyrimidin-2-ylpiperidin-4-yl)amino]acetyl]pyrrolidine-2-carbonitrile |
| Canonical SMILES | CC1(CCN(CC1)C2=NC=CC=N2)NCC(=O)N3CCCC3C#N |
| 分子式 | C17H24N6O |
| 分子量 | 328.41 |
| 溶解度 | <32.84mg/ml in DMSO;<16.42mg/ml in 1eq. HCl |
| 储存条件 | Desiccate at 4℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Dipeptidyl peptidase IV inhibitor. Inhibits rat, canine, human and monkey enzymes with IC50values of 3, 5, 8, and 8 nM respectively. Long-acting hypoglycemic agent; attenuates glucose excursion following glucose loading in Zucker fatty rats. |
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