Cas No. | 866396-34-1 |
化学名 | (2S,5R)-1-(2-((1-(hydroxymethyl)cyclopentyl)amino)acetyl)pyrrolidine-2,5-dicarbonitrile hydrochloride |
Canonical SMILES | OCC1(NCC(N2[C@H](C#N)CC[C@@H]2C#N)=O)CCCC1.Cl |
分子式 | C14H20N4O2.HCl |
分子量 | 312.8 |
溶解度 | <31.28mg/ml in DMSO;<15.64mg/ml in Water |
储存条件 | Desiccate at RT |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Inhibitor of dipeptidyl peptidase IV (DPP-IV) (IC50= 104 nM) that displays selectivity over enzymes with DPP-like activity (IC50> 30 μM). Increases plasma GLP-1 levels and improves glucose tolerance in diabetic mice following oral glucose challenge. |