CP 471474 是一种具有口服活性的泛 MMP 抑制剂，IC50 值为 1170 nM (MMP-1)、0.7 nM (MMP-2)、16 nM (MMP-3)、13 nM (MMP-9) 和 0.9 nM ( MMP-13），分别。
| Cas No. | 210755-45-6 |
| 别名 | 2-[[[4-(4-氟苯氧基)苯基]磺酰基]氨基]-N-羟基-2-甲基丙酰胺 |
| 化学名 | 2-[[4-(4-fluorophenoxy)phenyl]sulfonylamino]-N-hydroxy-2-methylpropanamide |
| Canonical SMILES | CC(C)(C(=O)NO)NS(=O)(=O)C1=CC=C(C=C1)OC2=CC=C(C=C2)F |
| 分子式 | C16H16FN2O5S |
| 分子量 | 368.38 |
| 溶解度 | <36.84mg/ml in DMSO |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Broad spectrum MMP inhibitor (IC50values are 0.7, 0.9, 13, 16 and 1170 nM for MMP-2, MMP-13, MMP-9, MMP-3 and MMP-1 respectively). Attenuates early left ventricular dilation after experimental myocardial infarction in mice. |
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