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Calcitonin(salmon)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Calcitonin(salmon)图片
CAS NO:47931-85-1
包装:10 mg
市场价:2995元

产品名称
Calcitonin salmon
鲑降钙素
Salmon calcitonin
产品介绍
Calcitonin salmon 是一种阿米林和卡西宁受体的双激动剂,是一种钙调节激素,能够刺激骨的生成并能抑制骨吸收。

产品描述

Calcitonin salmon, a calcium regulating hormone, is used to treat osteoporosis in women who are at least 5 years past menopause.

体内活性

Oral Calcitonin salmon treatment attenuates fasting and non-fasted hyperglycaemia during the intervention period in a dose-dependent manner. At the end of the study period, oral Calcitonin salmon treatment by dose decreases diabetic hyperglycaemia by ~9 mM and reduces HbA1c levels by 1.7%. Moreover, a pronounced reduction in glucose excursions is dose-dependently observed for oral Calcitonin salmon treatment during oral glucose tolerance test. In addition, oral Calcitonin salmon treatment sustains hyperinsulinaemia and attenuates hyperglucagonaemia and hypersecretion of total glucagon-like peptide-1 predominantly in the basal state. Lastly, oral Calcitonin salmon treatment dose-dependently improves pancreatic beta-cell function and beta-cell area at study end[1].

Cas No.

47931-85-1

分子式

C145H240N44O48S2

分子量

3431.85

别名

Calcitonin salmon;鲑降钙素;Salmon calcitonin

储存和溶解度

H2O:50 mg/mL (14.57 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years