BMS-986176 是一种有效的AAK1 抑制剂，IC50为 2.2 nM。BMS-986176在神经退行性疾病中有研究的价值。

AAK1-IN-1 is a highly selective and potent inhibitor of adaptor associated kinase 1 (AAK1, IC50 = 2 nM).

AAK1-IN-1can be used for neurodegenerative disease studies. Adaptor associated kinase 1 (AAK1) is a member of the Arkl/Prkl family of serine/threonine kinases and modulates clatherin coated endocytosis. and receptor-mediated endocytosis[1].

1815613-42-3

C19H23F4N3O

385.407

DMSO:220 mg/mL (570.84 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years