| CAS NO: | 57477-39-1 |
| 规格: | ≥98% |
| 包装 | 价格(元) |
| 25mg | 电议 |
| 50mg | 电议 |
| 100mg | 电议 |
| 250mg | 电议 |
| 500mg | 电议 |
| Molecular Weight (MW) | 230.31 |
|---|---|
| Formula | C14H18N2O |
| CAS No. | 57477-39-1 |
| Storage | -20℃ for 3 years in powder form |
| -80℃ for 2 years in solvent | |
| Solubility (In vitro) | DMSO: 46 mg/mL (199.7 mM) |
| Water: <1 mg/mL | |
| Ethanol: 2 mg/mL (8.7 mM) | |
| Solubility (In vivo) | 30% Propylene glycol, 5% Tween 80, 65% D5W: 30 mg/mL |
| Synonyms | BRL 54443; BRL54443; BRL-54443 |
| In Vitro | In vitro activity: BRL 54443 has also measurable affinity for the 5-HT2A receptor. BRL 54443 induces contraction with a –logEC50 of 6.52. Contraction caused by BRL 54443 is likely mediated through stimulation of 5-HT5-HT2A receptors. |
|---|---|
| In Vivo | BRL 54443 induces an immediate dose-dependent maximal intragastric volume increase vs. saline. |
| Animal model | Adult male cats |
| Formulation & Dosage | Dissolved in distilled water containing 1 equivalent 2,3-dihydroxybutanedioic acid+0.9% NaCl; 3 μg/kg-30 mg/kg; s.c.injection |
| References | Eur J Pharmacol. 2004 May 25;492(2-3):259-67; J Pharmacol Exp Ther. 2001 Apr;297(1):88-95. |
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