UNC0379 是一种选择性的、底物竞争性的赖氨酸甲基转移酶 SETD8 抑制剂，IC50值为 7.3 μM，也选择性抑制其他 15 种甲基转移酶。
产品描述
UNC0379 is a selective, substrate-competitive inhibitor of the lysine methyltransferase SETD8.
体外活性
UNC0379 is competitive with the peptide substrate and noncompetitive with the cofactor SAM. [1]
Cas No.
1620401-82-2
分子式
C23H35N5O2
分子量
413.566
储存和溶解度
DMSO:76 mg/mL (183.8 mM)
H2O:<1 mgml
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
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