Procainamide hydrochloride 是一种用于研究心律失常的抗心律失常制剂。

Procainamide Hydrochloride is the hydrochloride salt form of procainamide, an amide derivative exhibiting class 1A antiarrhythmic property and analog of procaine. Procainamide hydrochloride reversibly binds to and blocks activated (open) voltage-gated sodium channels, thereby blocks the influx of sodium ions into the cell, which leads to an increase in threshold for excitation and inhibit depolarization during phase 0 of the action potential.

614-39-1

C13H22ClN3O

271.79

Pronestyl;Procanbid;盐酸普鲁卡因胺;Procapan;Procainamide HCl

DMSO:198.7 mM
H2O:183.97mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years