ML251 是一种有效的新型纳摩尔 T. brucei 和 T. cruzi 磷酸果糖激酶抑制剂，对 T. brucei PFK 和 T. cruzi PFK 的IC50值为 0.37和 0.13 μM，可研究寄生虫。

ML251 is a potent novel nanomolar inhibitor of T. brucei and T. cruzi phosphofructokinase[1]. ML251 inhibits T. brucei PFK (IC50=0.37 μM) and T. cruzi PFK (IC50=0.13 μM). ML251 can be used for the research of parasite[1].

ML251 produces modest dose-dependent toxicity[1].

The cell cytotoxicity assay of ML251 (0~33.3 μg/mL) in T. brucei cell shows dose-dependent reduction of cell viability[1].

1486482-16-9

C17H13Cl2N3O4S

426.27

DMSO:249 mg/mL (584.13 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years